Indications:
The dosage of D-dimer is an aid in the diagnosis of venous thrombosis formed, phlebitis as pulmonary embolism.
This examination is also useful when in doubt about a diagnosis of disseminated intravascular coagulation.
Principle:
Degradation product of fibrin, D-dimer in the plasma appears in a non-physiological activation of coagulation.
Technique:
5 mL sample of blood sodium citrate; it can be done on the tube used for the construction and measuring fibrinogen.
the dosage is through fast, slide, or longer, ELISA.
Results:
Whatever the reagents used, the rate is, in any case, normally less than 500 mcg / L.
A higher rate is observed:
– If formed venous thrombosis, hematoma or cancer;
– During the thrombolytic therapy.
Normal levels of D-dimer eliminates the diagnosis of venous thrombosis and pulmonary embolism if the analysis was performed by ELISA, spreading blade being on him, insensitive.
Cost:
B30.
Practical advice:
After air travel lasting more than 4 hours in any discomfort, any pathology nonexistent until then, we should mention venous thrombosis or pulmonary embolism, and request a determination of D-dimer.
However, postoperative, the review has no diagnostic value.
Prevention is key: during a trip extended plane, advisor to small movements of the feet (extension, flexion), wearing stockings, drinking lots to prevent thrombosis.
